Directory of Madelung's Disease Resources

Home > Health > Conditions and Diseases > Nutritional and Metabolic Disorders > Inherited > Madelung's Disease

Madelung's Disease (also called Multiple Symmetrical Lipomatosis [MSL], Benign Symmetric Lipomatosis or Lanois-Bensaude Syndrome) is a metabolic condition characterized by the growth of fatty masses around the face, back of the head, neck, upper arms, abdomen, back and upper leg in a very specific pattern or distribution. Unlike the usual lipoma, these benign, fatty masses are not enclosed within a membranous capsule with very distinct boundaries. It is because of this characteristic, as well as the absolute symmetry in their occurrence, that the condition is often dismissed as simple obesity.

Resources in This Category

• Dermatology Online Journal: Familial Multiple Lipomatosis

  http://escholarship.org/uc/item/7088d8pk
  Article by Brian R Toy, MD on this rare hereditary syndrome with the case history of an 89 year old man.

• Lipomatosi di Launois-Bensaude (MSL)

  http://digilander.libero.it/camdic/LBS.html
  A site, in both Italian and English, providing a historical perspective of Madelung's Disease.

• Madelung's Disease

  http://www.cushings-help.com/madelung.htm
  Describes the symptoms and diagnostic techniques for Madelung's disease, emphasizing the peculiarities of the disease compared to normal fatty deposits.

• Madelung's Disease: Inherited from an Ancient Mediterranean Population?

  http://www.nejm.org/doi/full/10.1056/NEJM199905133401906
  Abstract of a case study in the New England Journal of Medicine. Full text available for purchase.

• NORD: Madelung's Disease

  http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Madelung's+Disease
  The National Organization for Rare Disorders briefly describes this rare disorder (also known as Multiple Symmetrical Lipomatosis, Benign Symmetric Lipomatosis or Lanois-Bensaude Syndrome) and lists further reference information.

• OMIM Entry 151800

  http://omim.org/entry/151800
  Describes the form of Multiple Symmetric Lipomatosis (MSL) characterized by a collar of fat around the neck. The article suggests the cause to be a mitochondrial abnormality.

• Osteonecrosis in multiple symmetrical lipomatosis

  http://www.eurorad.org/eurorad/case.php?id=1405
  The European Association of Radiology presents an illustrated case history from the Royal Liverpool University Hospital.

• Soft Tissue Pathology

  http://www.cuhk.edu.hk/med/paf/slides/soft/soft.htm
  Features images of the disease, taken with various scanning techniques.

Related Categories

• Home > Health > Conditions and Diseases > Lipomas
• Home > Health > Conditions and Diseases > Skin Disorders > Dercum Disease

 

Home > Health > Conditions and Diseases > Nutritional and Metabolic Disorders > Inherited > Madelung's Disease

 

---

 

Thanks to DMOZ, which built a great web directory for nearly two decades and freely shared it with the web. About us